Muscarinic Receptor: From Structure to Animal Models

<p>Towards the Crystal Structure Determination of Muscarinic Acetylcholine Receptors.- Homology Modeling and Docking Evaluation of Human Muscarinic Acetylcholine Receptors.- Radioligand Binding at Muscarinic Receptors.- Binding Method for Detection of Muscarinic Acetylcholine Receptors in Receptor’s Natural Environment.- Use of Antibodies in the Research on Muscarinic Receptor Subtypes.- Allosteric Modulation of Muscarinic Receptors.- Subcellular and Synaptic Localization of Muscarinic Receptors in Neurons Using High-Resolution Electron Microscopic Preembedding Immunogold Technique.- Investigation of Muscarinic Receptors by Fluorescent Techniques.- Autoradiography Assessment of Muscarinic Receptors in the Central Nervous System.- Imaging of Muscarinic Receptors in the Central Nervous System.- Detection of Non-Neuronal Acetylcholine.- Utilization of Superfused Cerebral Slices in Probing Muscarinic Receptor Autoregulation of Acetylcholine Release.- Regulation of Heart Contractility by M₂ and M₃ Muscarinic Receptors: Functional Studies using Muscarinic Receptor Knockout Mouse.- Muscarinic Receptor Gene Transfections and In Vivo Dopamine Electrochemistry: Muscarinic Receptor Control of Dopamine-Dependent Reward and Locomotion.</p>